Skunk #1, also known as “#1” or simply as “Skunk,” remains one of the most famous strains of all time, born three decades ago in Holland, where breeders crossed multiple strains from South and Central America, Thailand, and Afghanistan. The result became a staple in itself and spawned countless hybrids containing its genes. True to its name, Skunk #1 smells decidedly skunky, while the taste is a mix of sour and earthy flavours. This is an indica-dominant strain (35:65 sativa/indica ratio) best used late in the day. Though it comes with a head buzz that belies its indica genes, Skunk #1 also provides deep-body relaxation. The head high is energetic and creative, while the body high is peaceful and soothing. It can be used to treat anxiety and other mental disorders, as well as chronic pain, headaches, and lack of appetite. This strain remains highly popular in Amsterdam, and though it can be found across the United States, it’s mostly found on the West Coast, Arizona, and Colorado. Dry mouth is the most common problem associated with this strain, as well as paranoia and red eyes.